BDBM391818 1-((R)-3-(4-amino-3-(2-fluoro-4-(2- fluorobenzoyl)phenyl)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US10300066, Compound 72

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4F)cc3F)c12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=ZGAAKKQVGDXJKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 391818   

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM391818(US10300066, Compound 72 | 1-((R)-3-(4-amino-3-(2-f...)
Affinity DataIC50: 1nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent