BDBM392638 N-((6-amino-2-methylpyridin-3- yl)methyl)-1-((3-chloroquinolin-6- yl)methyl)-5-oxo-4,5-dihydro-1H- pyrrolo[3,2-b]pyridine-3-carboxamide::US10301284, Example 125::US10781200, Example 125

SMILES Cc1nc(N)ccc1CNC(=O)c1cn(Cc2ccc3ncc(Cl)cc3c2)c2ccc(=O)[nH]c12

InChI Key InChIKey=IWDBVKCJUBGXNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392638   

TargetPlasma kallikrein(Human)
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM392638(N-((6-amino-2-methylpyridin-3- yl)methyl)-1-((3-ch...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM392638(N-((6-amino-2-methylpyridin-3- yl)methyl)-1-((3-ch...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent