BDBM393373 3-((4-(2-Methoxypyridin-3-yl)benzyl)oxy)azetidine-1-carbonitrile::US9963444, Example 74
SMILES COc1ncccc1-c1ccc(COC2CN(C2)C#N)cc1
InChI Key InChIKey=SPXOXHNZZYXODQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 393373
Affinity DataIC50: 5.80nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair