BDBM393440 N-(5-((2S,5R,6S)-5-amino-6- fluorooxepan-2-yl)-1H-pyrazol- 4-yl)-2-(3-methylpyridin-2- yl)thiazole-4-carboxamide::US9963446, Example 128

SMILES Cc1cccnc1-c1nc(C(=O)Nc2cn[nH]c2[C@@H]2CC[C@@H](N)[C@H](F)CO2)cs1

InChI Key InChIKey=XHIMTRQOZBMLJT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393440   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 393440BDBM393440(US9963446, Example 128 | N-(5-((2S,5R,6S)-5-amino-...)
Affinity DataKi:  0.777nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent