BDBM393932 US9969749, Example 1-25::trans-N,N-dimethyl-N'- [6-(pyrimidin-5- yl)quinazolin-4- yl]cyclohexane-1,4- diamine

SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)-c1cncnc1

InChI Key InChIKey=YLWVDHIGQPHUEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393932   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393932(US9969749, Example 1-25 | trans-N,N-dimethyl-N'- [...)
Affinity DataIC50: 3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent