BDBM394326 US10428087, Example 46::US10829502, Example 46::US9975907, Example 46

SMILES Cc1csc2nc([C@H](C)Nc3ccnc4[nH]cnc34)c(-c3cccc(F)c3)c(=O)n12

InChI Key InChIKey=HPRYVHBFWOKYRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394326   

LigandChemical structure of BindingDB Monomer ID 394326BDBM394326(US9975907, Example 46 | US10428087, Example 46 | U...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394326BDBM394326(US9975907, Example 46 | US10428087, Example 46 | U...)
Affinity DataIC50: 50nMAssay Description:Assay A2: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume of 24 μL. Inhibitors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394326BDBM394326(US9975907, Example 46 | US10428087, Example 46 | U...)
Affinity DataIC50: 50nMAssay Description:Example A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent