BDBM395290 N-[2-(2-Hydroxyethyl)-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide::US10308634, Example 5::US10793545, Example 5::US11992481, Example 5::US12006303, Example 5
SMILES CC(C)(O)c1cc2nn(CCO)cc2cc1NC(=O)c1cccc(n1)C(F)(F)F
InChI Key InChIKey=WZNSJHMKGMYSPA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 395290
Affinity DataIC50: 264nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...More data for this Ligand-Target Pair
Affinity DataIC50: 264nMAssay Description:The IRAK4-inhibitory activity of the inventive substances was measured in the IRAK4 TR-FRET assay (TR-FRET=Time Resolved Fluorescence Resonance Energ...More data for this Ligand-Target Pair
Affinity DataIC50: 264nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
Affinity DataIC50: 264nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...More data for this Ligand-Target Pair