BDBM395538 (R)-1-((7-chloro-2-(3′-((2-chloro-5-((5-cyanopyridin-3-yl)methoxy)-4-(((2-hydroxyethyl)amino)methyl)phenoxy)methyl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid::US10308644, Example 150::US10800768, Example 150::US11339149, Example 150

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CNCCO)cc2Cl)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(Cl)c3o2)c1C

InChI Key InChIKey=YQCJWJZNBBONQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395538   

LigandPNGBDBM395538((R)-1-((7-chloro-2-(3′-((2-chloro-5-((5-cyan...)
Affinity DataIC50: 55nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395538((R)-1-((7-chloro-2-(3′-((2-chloro-5-((5-cyan...)
Affinity DataIC50: 55nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395538((R)-1-((7-chloro-2-(3′-((2-chloro-5-((5-cyan...)
Affinity DataIC50: 750nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent