BDBM395603 (R)-1-((8-(3'-(7- cyano-5-((3- hydroxypyrrolidin- 1-yl)methyl)benzo- [d]oxazol-2-yl)-2,2'- dimethyl biphenyl- 3-ylamino)-1,7-::US10308644, Example 214::US10800768, Example 214::US11339149, Example 214

SMILES Cc1c(Nc2nccc3cc(CN4CCCCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@@H](O)C4)cc(C#N)c3o2)c1C

InChI Key InChIKey=YJYKSYFURREOPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395603   

LigandPNGBDBM395603(US10308644, Example 214 | (R)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395603(US10308644, Example 214 | (R)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395603(US10308644, Example 214 | (R)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent