BDBM395605 (R)-1-((8-(3'-(7- cyano-5-(((R)-3- hydroxypyrrolidin- 1-yl)methyl)benzo [d]oxazol-2-yl)- 2,2'-dimethyl- biphenyl-3- ylamino)-1,7-::US10308644, Example 216::US10800768, Example 216::US11339149, Example 216

SMILES C[C@H]1CCN(Cc2cnc3c(Nc4cccc(c4C)-c4cccc(-c5nc6cc(CN7CC[C@@H](O)C7)cc(C#N)c6o5)c4C)nccc3c2)C1

InChI Key InChIKey=UBXGLNULNLZWRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395605   

LigandPNGBDBM395605(US10308644, Example 216 | (R)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395605(US10308644, Example 216 | (R)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395605(US10308644, Example 216 | (R)-1-((8-(3'-(7- cyano-...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent