BDBM395607 (R)-1((7-cyano-2- (3'-(5-(2-(ethyl- (methyl)amino)- acetyl)-5,6-dihydro- 4H-pyrrolo[3,4- d]thiazol-2-yl)- 2,2'-dimethyl- biphenyl-3-yl)- benzo[d]oxazol- 5-yl)methyl)-3- methylpyrrolidine- 3-carboxylic acid::US10308644, Example 218::US10800768, Example 218::US11339149, Example 218

SMILES CCN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=XGVYXQMZCSQNFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395607   

LigandPNGBDBM395607(US10308644, Example 218 | (R)-1((7-cyano-2- (3'-(5...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395607(US10308644, Example 218 | (R)-1((7-cyano-2- (3'-(5...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395607(US10308644, Example 218 | (R)-1((7-cyano-2- (3'-(5...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent