BDBM395613 (R)-1-((7-cyano- 2-(3'-(5-(2-((2- hydroxyethyl) (methyl)amino)- acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- thiazol-2-yl)- 2,2'-dimethyl- biphenyl-3-yl)- benzo[d]oxazol- 5-yl)methyl)-3-::US10308644, Example 224::US10800768, Example 224::US11339149, Example 224

SMILES CN(CCO)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=ZQPIFZQZUWIUGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395613   

LigandPNGBDBM395613(US10308644, Example 224 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395613(US10308644, Example 224 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395613(US10308644, Example 224 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent