BDBM395616 (R)-1-((7-cyano- 2-(3'-(5-(2-(3- hydroxyazetidin- 1-yl)acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- thiazol-2-yl)-2,2'- dimethylbiphenyl- 3-yl)benzo[d]- oxazol-5-yl)methyl)- 3-methylpyrrolidine-::US10308644, Example 227::US10800768, Example 227::US11339149, Example 227

SMILES Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC(O)C2)c1C)-c1nc2cc(CN3CC[C@](C)(C3)C(O)=O)cc(C#N)c2o1

InChI Key InChIKey=XIWVNVPTRQGQIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395616   

LigandPNGBDBM395616(US10308644, Example 227 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395616(US10308644, Example 227 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395616(US10308644, Example 227 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent