BDBM395620 2-((7-cyano-2-(3'- (5-(2-((2-hydroxy- ethyl)(methyl)- amino)acetyl)-5,6- dihydro-4H-pyrrolo- [3,4-d]thiazol-2-yl)- 2,2'-dimethyl- biphenyl-3-yl)benzo- [d]oxazol-5-yl)- methyl)-2-azaspiro- [3.3]heptane-6- carboxylic acid::US10308644, Example 230::US10800768, Example 230::US11339149, Example 230

SMILES CN(CCO)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5(CC(C5)C(O)=O)C4)cc(C#N)c3o2)c1C

InChI Key InChIKey=RGALMMJRAGXMSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395620   

LigandPNGBDBM395620(US10308644, Example 230 | 2-((7-cyano-2-(3'- (5-(2...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395620(US10308644, Example 230 | 2-((7-cyano-2-(3'- (5-(2...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395620(US10308644, Example 230 | 2-((7-cyano-2-(3'- (5-(2...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent