BDBM395623 2-((7-cyano-2-(3'- (5-(2-((S)-3-hydroxy- pyrrolidin-1-yl)- acetyl)-5,6-dihydro- 4H-pyrrolo[3,4-d]- thiazol-2-yl)-2,2'- dimethylbiphenyl- 3-yl)benzo[d]oxazol- 5-yl)methyl)-2- azaspiro[3.3]heptane- 6-carboxylic acid::US10308644, Example 233::US10800768, Example 233::US11339149, Example 233

SMILES Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@H](O)C2)c1C)-c1nc2cc(CN3CC4(CC(C4)C(O)=O)C3)cc(C#N)c2o1

InChI Key InChIKey=AGPGTTUMITYCLE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395623   

LigandPNGBDBM395623(US10308644, Example 233 | 2-((7-cyano-2-(3'- (5-(2...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395623(US10308644, Example 233 | 2-((7-cyano-2-(3'- (5-(2...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395623(US10308644, Example 233 | 2-((7-cyano-2-(3'- (5-(2...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent