BDBM395627 2-((7-cyano-2- (3'-(5-(2- (dimethyl- amino)acetyl)- 5,6-dihydro- 4H-pyrrolo[3,4- d]thiazol-2-yl)- 2,2'-dimethyl- biphenyl-3-yl)- benzo[d]oxazol- 5-yl)methyl)-2-::US10308644, Example 237::US10800768, Example 237::US11339149, Example 237

SMILES CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC5CC4CC5C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=WKIFBCFSQTZWMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395627   

LigandPNGBDBM395627(US10308644, Example 237 | 2-((7-cyano-2- (3'-(5-(2...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395627(US10308644, Example 237 | 2-((7-cyano-2- (3'-(5-(2...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395627(US10308644, Example 237 | 2-((7-cyano-2- (3'-(5-(2...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent