BDBM395629 1-((2-(2′-chloro-3′-(6-isopropyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-2-yl)-2-methylbiphenyl-3-yl)-7-cyanobenzo[d]oxazol-5-yl)methyl)azetidine-3-carboxylic acid::US10308644, Example 239::US10800768, Example 239::US11339149, Example 239

SMILES CC(C)N1CCc2cn(nc2C1)-c1cccc(c1Cl)-c1cccc(-c2nc3cc(CN4CC(C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=VXCWPCQGPNEXAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395629   

LigandPNGBDBM395629(US10308644, Example 239 | 1-((2-(2′-chloro-3...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395629(US10308644, Example 239 | 1-((2-(2′-chloro-3...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395629(US10308644, Example 239 | 1-((2-(2′-chloro-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent