BDBM395630 (R)-4-((2-(2-chloro-3′-(7-cyano-5-((3-hydroxypyrrolidin-1-yl)methyl)benzo[d]oxazol-2-yl)-2′-methylbiphenyl-3-ylcarbamoyl)-1-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methyl)phenylboronic acid::US10308644, Example 240::US10800768, Example 240::US11339149, Example 240

SMILES Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(Cc4ccc(cc4)B(O)O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1

InChI Key InChIKey=FLFZQDBPCLOKEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395630   

LigandPNGBDBM395630(US10308644, Example 240 | (R)-4-((2-(2-chloro-3...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395630(US10308644, Example 240 | (R)-4-((2-(2-chloro-3...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395630(US10308644, Example 240 | (R)-4-((2-(2-chloro-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent