BDBM395634 1-((7-cyano-2-(3'- (5-(N-ethyl-N- methylglycyl)- 5,6-dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)-2,2'- dimethyl-[1,1'- biphenyl]-3-yl)- benzo[d]oxazol- 5-yl)methyl)- piperidine-4-::US10308644, Example 244::US10800768, Example 244::US11339149, Example 244

SMILES CCN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=AELAMVNAXVUNEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395634   

LigandPNGBDBM395634(US10308644, Example 244 | 1-((7-cyano-2-(3'- (5-(N...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395634(US10308644, Example 244 | 1-((7-cyano-2-(3'- (5-(N...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395634(US10308644, Example 244 | 1-((7-cyano-2-(3'- (5-(N...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent