BDBM395636 1-((7-cyano-2-(3'- (5-(dimethylglycyl)- 5,6-dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)-2,2'- dimethyl-[1,1'- biphenyl]-3-yl)- benzo[d]oxazol- 5-yl)methyl)- piperidine-4- carboxylic acid::US10308644, Example 246::US10800768, Example 246

SMILES CN(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=WIXROFUMKKLENV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395636   

LigandPNGBDBM395636(US10308644, Example 246 | 1-((7-cyano-2-(3'- (5-(d...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395636(US10308644, Example 246 | 1-((7-cyano-2-(3'- (5-(d...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent