BDBM395640 (R)-1-((7-cyano- 2-(3'-(5-(2-(4- hydroxypiperidin- 1-yl)acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)-2,2'- dimethyl-[1,1'- biphenyl]-3-yl)- benzo[d]oxazol- 5-yl)methyl)-::US10308644, Example 250::US10800768, Example 250::US11339149, Example 250

SMILES Cc1c(cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C)-c1nc2CN(Cc2o1)C(=O)CN1CCC(O)CC1

InChI Key InChIKey=SFZNIMFLAXFPBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395640   

LigandPNGBDBM395640(US10308644, Example 250 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395640(US10308644, Example 250 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395640(US10308644, Example 250 | (R)-1-((7-cyano- 2-(3'-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent