BDBM395643 2-((7-cyano-2-(2,2'- dimethyl-3,-(5-(2- (4-methylpiperazin- 1-yl)acetyl)-5,6- dihydro-4H-pyrrolo- [3,4-d]oxazol-2-yl)- [1,1'-biphenyl]-3- yl)benzo[d]oxazol- 5-yl)methyl)-2- azabicyclo[2.2.1]-::US10308644, Example 253::US10800768, Example 253::US11339149, Example 253

SMILES CN1CCN(CC(=O)N2Cc3nc(oc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC6CC5CC6C(O)=O)cc(C#N)c4o3)c2C)CC1

InChI Key InChIKey=JSLMKZWIFWGPNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395643   

LigandPNGBDBM395643(US10308644, Example 253 | 2-((7-cyano-2-(2,2'- dim...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395643(US10308644, Example 253 | 2-((7-cyano-2-(2,2'- dim...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395643(US10308644, Example 253 | 2-((7-cyano-2-(2,2'- dim...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent