BDBM395681 US10308645, Example 20::methyl 2-({(2R,5R)-5-[5-(1-hydroxy-1- methylethyl)-1,2,4-oxadiazol-3-yl]-2- methylpiperidin-1-yl}carbonyl)benzoate

SMILES COC(=O)c1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)c1noc(n1)C(C)(C)O

InChI Key InChIKey=AGPOBLCNTFOEAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395681   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM395681(US10308645, Example 20 | methyl 2-({(2R,5R)-5-[5-(...)
Affinity DataIC50: 97nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM395681(US10308645, Example 20 | methyl 2-({(2R,5R)-5-[5-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent