BDBM395718 N1-(4-(((1S,3R)-3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)cyclohexyl)carbamoyl)phenyl)oxalamide ::US10308648, Compound 113::US10865206, Compound 113

SMILES NC(=O)C(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=OLLSHBBSLYOHPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395718   

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395718(US10308648, Compound 113 | N1-(4-(((1S,3R)-3-((5-c...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395718(US10308648, Compound 113 | N1-(4-(((1S,3R)-3-((5-c...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent