BDBM395721 (+/−)-2-(4-(9-(2-(Difluoromethoxy)phenyl)-6,7,8,9-tetrahydropyrido [4′,3′:4,5]imidazo[1,2-b]pyridazin-2-yl)phenyl)propan-2-ol::US10308652, Example 2

SMILES CC(C)(O)c1ccc(cc1)-c1ccc2nc3CCNC(c3n2n1)c1ccccc1OC(F)F

InChI Key InChIKey=PCYTWKMNYMULRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395721   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM395721((+/−)-2-(4-(9-(2-(Difluoromethoxy)phenyl)-6,...)
Affinity DataIC50: <1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent