BDBM395855 5-tert-butyl-3-[5-cyclopropyl-4-(oxetan-3-yloxy)pyridin-2-yl]-1,2,4-oxadiazole::US10308659, Example 54

SMILES CC(C)(C)c1nc(no1)-c1cc(OC2COC2)c(cn1)C1CC1

InChI Key InChIKey=UQCMEDIOQVHRHB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395855   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 395855BDBM395855(5-tert-butyl-3-[5-cyclopropyl-4-(oxetan-3-yloxy)py...)
Affinity DataEC50:  33.1nMAssay Description:The affinity of the compounds of the invention for cannabinoid CB1 receptors was determined using recommended amounts of membrane preparations (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 395855BDBM395855(5-tert-butyl-3-[5-cyclopropyl-4-(oxetan-3-yloxy)py...)
Affinity DataEC50: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid CB1 receptors was determined using recommended amounts of membrane preparations (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent