BDBM396022 6-amino-2-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-5-(3-chloro-4-methylphenyl)-3-methylpyrimidin-4(3H)-one::US10308660, Example 123
SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(N)c(Sc3ccc(Cl)c(C)c3)c(=O)n2C)[C@@H]1N
InChI Key InChIKey=XAWYTSWCGJDSOA-SUMWQHHRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 396022
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair