BDBM396560 3-[5-Chloro-2-[2-(3-chloro-phenyl)-ethoxy]-phenoxy]-azetidine::US9981909, Example 185

SMILES Clc1cccc(CCOc2ccc(Cl)cc2OC2CNC2)c1

InChI Key InChIKey=WJADBJDMYMVZGL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 396560   

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396560(US9981909, Example 185 | 3-[5-Chloro-2-[2-(3-chlor...)
Affinity DataKi:  6nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396560(US9981909, Example 185 | 3-[5-Chloro-2-[2-(3-chlor...)
Affinity DataKi:  7nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396560(US9981909, Example 185 | 3-[5-Chloro-2-[2-(3-chlor...)
Affinity DataKi:  8nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396560(US9981909, Example 185 | 3-[5-Chloro-2-[2-(3-chlor...)
Affinity DataKi:  29nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396560(US9981909, Example 185 | 3-[5-Chloro-2-[2-(3-chlor...)
Affinity DataKi:  91nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 6(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396560(US9981909, Example 185 | 3-[5-Chloro-2-[2-(3-chlor...)
Affinity DataKi:  177nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent