BDBM396886 US9981950, Example 93

SMILES Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1

InChI Key InChIKey=NTXPVEQQFPXEPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396886   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM396886(US9981950, Example 93)
Affinity DataIC50: 1.20nMAssay Description:Cells were split 2-3 times weekly between 1:3 and 1:4. For binding assays and membrane preparations the cell culture medium was removed, cells were w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent