BDBM397141 US10456385, Example 46::US9987259, Example 46

SMILES CC(C)c1cnc(s1)-n1cc(ccc1=O)C(=O)OC1CN2CCC1CC2

InChI Key InChIKey=PIPNXLBARLRNDT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397141   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397141(US9987259, Example 46 | US10456385, Example 46)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397141(US9987259, Example 46 | US10456385, Example 46)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent