BDBM397186 US9988392, Compound 6

SMILES COc1ccc2c3c1O[C@H]1C4(OC)CC[C@@]5(C[C@]4(C)COCc4ccccc4)[C@@H](C2)N(CC2CC2)CC[C@]315

InChI Key InChIKey=VPYHVRQKZDMUFK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 397186   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397186BDBM397186(US9988392, Compound 6)
Affinity DataEC50:  0.0850nMAssay Description:κ-Opioid: Receptor Binding Assay Procedures: Membranes from HEK-293, CHO or U-2 OS cells expressing the recombinant human kappa opioid receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397186BDBM397186(US9988392, Compound 6)
Affinity DataEC50:  8.81nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397186BDBM397186(US9988392, Compound 6)
Affinity DataEC50:  57.7nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent