BDBM397467 (4R,4aS,6R,7R,7aR,12bS)-6-((benzylamino)methyl)-3-(cyclopropylmethyl)-7-methoxy-1,2,3,4,5,6,7,7a-octahydro-4a,7-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol ::US9988392, Compound 12

SMILES COC12CC[C@@]3(C[C@]1(C)CNCc1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45

InChI Key InChIKey=HCOMAJHQYOPOCF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 397467   

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM397467(US9988392, Compound 12 | (4R,4aS,6R,7R,7aR,12bS)-6...)
Affinity DataEC50:  3.39nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent