BDBM39766 4-Amino-3-(4-fluoro-phenyl)-isothiazole-5-carboxylic acid [cyclopentylcarbamoyl-(4-methoxy-phenyl)-methyl]-(3-fluoro-phenyl)-amide::4-amino-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-3-(4-fluorophenyl)-1,2-thiazole-5-carboxamide::4-amino-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-3-(4-fluorophenyl)-5-isothiazolecarboxamide::4-amino-N-[2-(cyclopentylamino)-2-keto-1-(4-methoxyphenyl)ethyl]-N-(3-fluorophenyl)-3-(4-fluorophenyl)isothiazole-5-carboxamide::4-azanyl-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxidanylidene-ethyl]-N-(3-fluorophenyl)-3-(4-fluorophenyl)-1,2-thiazole-5-carboxamide::MLS000568642::SMR000172979::cid_3192705

SMILES Cn4c(=O)n(C1CCC(=O)NC1=O)c3ccc2CCNCc2c34

InChI Key InChIKey=YDCVLNKBRGVWRS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 39766   

TargetProtein cereblon(Human)
Hainan Simcere Zaiming Pharmeceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 39766BDBM39766(US20260098043, Compound 8)
Affinity DataIC50: 8.70E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent