BDBM39776 4-({2-[(4-fluorobenzyl)oxy]benzyl}amino)benzenesulfonamide::4-[[2-(4-fluorobenzyl)oxybenzyl]amino]benzenesulfonamide::4-[[2-[(4-fluorophenyl)methoxy]phenyl]methylamino]benzenesulfonamide::MLS000540174::SMR000162554::cid_979801

SMILES CC(=O)Nc1cccc(-c2c(C)n([C@H]3CC[C@H](CC#N)CC3)c3c2cnc2ccsc23)c1

InChI Key InChIKey=XOQASPJLNQBBCW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 39776   

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39776BDBM39776(US20260098044, Example 4)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39776BDBM39776(US20260098044, Example 4)
Affinity DataIC50: 200nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent