BDBM39777 1-(2-Ethyl-phenyl)-3-(9-thiophen-2-ylmethyl-9-aza-bicyclo[3.3.1]non-3-yl)-thiourea::1-(2-ethylphenyl)-3-[9-(2-thenyl)-9-azabicyclo[3.3.1]nonan-3-yl]thiourea::1-(2-ethylphenyl)-3-[9-(thiophen-2-ylmethyl)-9-azabicyclo[3.3.1]nonan-3-yl]thiourea::MLS000556774::SMR000173331::cid_3218177

SMILES Cc1c(-c2ccnc(C(=O)N(C)C)c2)c2cnc3ccsc3c2n1[C@H]1CC[C@H](CC#N)CC1

InChI Key InChIKey=RTHWEWFPJIGDGA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 39777   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39777BDBM39777(US20260098044, Example 5)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39777BDBM39777(US20260098044, Example 5)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent