BDBM397978 US9994571, Compound 7

SMILES COc1ccc2[C@@H](O)[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CC[C@@]34O)NC(=O)NC5=O)c2c1

InChI Key InChIKey=PTDXYUZYOWUHPO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397978   

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM397978(US9994571, Compound 7)
Affinity DataKi: >2.00E+4nMAssay Description:μ-Opioid Receptor:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM397978(US9994571, Compound 7)
Affinity DataKi: >2.00E+4nMAssay Description:κ-Opioid: Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details
US Patent