BDBM397992 US9994571, Compound 16

SMILES O[C@H]1[C@H]2N(CC3CC3)CC[C@@]34[C@@H](Oc5c3c1ccc5O)[C@]1(CC[C@@]24O)NC(=O)NC1=O

InChI Key InChIKey=WDRLAKXNWGLAEH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397992   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM397992(US9994571, Compound 16)
Affinity DataKi: >2.00E+4nMAssay Description:κ-Opioid: Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM397992(US9994571, Compound 16)
Affinity DataKi: >2.00E+4nMAssay Description:μ-Opioid Receptor:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details
US Patent