BDBM398321 US10323018, Compound I-50::US10323018, Compound I-51

SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCC1CC1c1ncc[nH]1)-c1ccc(F)cc1

InChI Key InChIKey=NSKDHMJJQBKKMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 398321   

TargetNicotinamide phosphoribosyltransferase(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM398321(US10323018, Compound I-50 | US10323018, Compound I...)
Affinity DataIC50: 10nMAssay Description:To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM398321(US10323018, Compound I-50 | US10323018, Compound I...)
Affinity DataIC50: 30nMAssay Description:To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent