BDBM398530 1-(3-cyclopropyl-1-phenyl- 1H-pyrazol-5-yl)-3-(trans- 1-(2-methoxyethyl)-4- phenylpyrrolidin-3-yl)urea::US10323022, Example 9

SMILES COCCN1C[C@@H](NC(=O)Nc2cc(nn2-c2ccccc2)C2CC2)[C@@H](C1)c1ccccc1

InChI Key InChIKey=RJDHMHQMANTTFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398530   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 398530BDBM398530(US10323022, Example 9 | 1-(3-cyclopropyl-1-phenyl-...)
Affinity DataIC50: 100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent