BDBM399957 US10323042, Example 37::US10738063, Example 37

SMILES CNC(=O)c1nn2CCCOc2c1-c1cc(F)c(Cl)cc1C

InChI Key InChIKey=XWLDNGLNMIBYMP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 399957   

LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  918nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  363nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  854nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  1.18E+4nMAssay Description:A portion of the human PDE4D3 coding sequence (amino acids 50 to 672 from the sequence with accession number Q08499-2) was cloned into the baculoviru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  918nMAssay Description:Human PDE4B1 coding sequence (amino acids 122 to 736 from the sequence with accession number Q07343) with the mutations resulting in the amino acid s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  363nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  854nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM399957(US10323042, Example 37 | US10738063, Example 37)
Affinity DataIC50:  1.18E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent