BDBM400099 7-(2-((1-(1H-1,2,3-triazol-4-yl)cyclopropyl)amino)-2-oxoacetyl)-N-(3-(difluoromethyl)-4-fluorophenyl)-6-methyl-2,3-dihydro-1H-pyrrolizine-5-carboxamide::US10328053, Compound 77::US10874640, Compound 77::US20230270719, Compound 77

SMILES Cc1c(C(=O)C(=O)NC2(CC2)c2c[nH]nn2)c2CCCn2c1C(=O)Nc1ccc(F)c(c1)C(F)F

InChI Key InChIKey=VQRNQBREMXXKTN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400099   

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM400099(US10328053, Compound 77 | 7-(2-((1-(1H-1,2,3-triaz...)
Affinity DataEC50:  19nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent

TargetSodium/bile acid cotransporter(Human)
Gilead Sciences

US Patent
LigandPNGBDBM400099(US10328053, Compound 77 | 7-(2-((1-(1H-1,2,3-triaz...)
Affinity DataEC50:  19nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetSodium/bile acid cotransporter(Human)
Gilead Sciences

US Patent
LigandPNGBDBM400099(US10328053, Compound 77 | 7-(2-((1-(1H-1,2,3-triaz...)
Affinity DataEC50:  19nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent