BDBM4005 1 H-indole-3-alkanamide deriv. 10n::2,2 -Dithiobis[N-[(4-carboxy-3-hydroxyphenyl)methyl]-1H-indole-3-propanamide]::4-{[3-(2-{[3-(2-{[(4-carboxy-3-hydroxyphenyl)methyl]carbamoyl}ethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanamido]methyl}-2-hydroxybenzoic acid

SMILES OC(=O)c1ccc(CNC(=O)CCc2c(SSc3[nH]c4ccccc4c3CCC(=O)NCc3ccc(C(O)=O)c(O)c3)[nH]c3ccccc23)cc1O

InChI Key InChIKey=KUKWJPKUERJESV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4005   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4005(2,2 -Dithiobis[N-[(4-carboxy-3-hydroxyphenyl)methy...)
Affinity DataIC50: 8.50E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed