BDBM400839 2-Amino-N-{5-[(3R)-3-aminopiperidin-1-yl]-1-methyl-1H-pyrazol-4-yl}thieno[3,2-b]pyridine-3-carboxamide::US10000507, Example 3

SMILES Cn1ncc(NC(=O)c2c(N)sc3cccnc23)c1N1CCC[C@@H](N)C1

InChI Key InChIKey=JIWSWLFCPVKNSD-SNVBAGLBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400839   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM400839(2-Amino-N-{5-[(3R)-3-aminopiperidin-1-yl]-1-methyl...)
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM400839(2-Amino-N-{5-[(3R)-3-aminopiperidin-1-yl]-1-methyl...)
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM400839(2-Amino-N-{5-[(3R)-3-aminopiperidin-1-yl]-1-methyl...)
Affinity DataIC50: >2.00E+3nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent