BDBM401285 US10005756, Compound A52

SMILES NC(=O)CC[C@H](NC(=O)c1cc2cc(ccc2[nH]1)N1CC[C@](O)(C(=O)NCc2cc(F)cc(Cl)c2)C1=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=PPPMYIPWPDZXNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401285   

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401285(US10005756, Compound A52)
Affinity DataIC50: 75nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent