BDBM401288 US10005756, Compound A58

SMILES O[C@@]1(CCN(C1=O)c1ccc2n(ccc2c1)S(=O)(=O)c1ccccc1)C(=O)NCc1cc(F)cc(F)c1

InChI Key InChIKey=OXGJUCFALVHZOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401288   

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401288(US10005756, Compound A58)
Affinity DataIC50: 160nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent