BDBM401305 US10005756, Compound A76

SMILES COc1ccc(Cn2ccc3cc(cnc23)N2CC[C@](O)(C(=O)NCc3cc(F)cc(F)c3)C2=O)cc1

InChI Key InChIKey=VWYJSRWSUFDSNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401305   

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401305(US10005756, Compound A76)
Affinity DataIC50: 150nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent