BDBM401312 US10005756, Compound A83

SMILES NC(=O)c1ccc2cc(ccc2n1)N1CCC(O)(C(=O)NCc2cc(F)cc(Cl)c2)C1=O

InChI Key InChIKey=IRQDMLPQHXKKJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401312   

TargetMethionine aminopeptidase 2(Human)
Merck Patent

US Patent
LigandPNGBDBM401312(US10005756, Compound A83)
Affinity DataIC50: 170nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent