BDBM4015 1 H-indole-3-alkanamide deriv. 11j::N-benzyl-3-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)propanamide

SMILES O=C(CCC1C(=S)Nc2ccccc12)NCc1ccccc1

InChI Key InChIKey=FRECTLXXXNGYET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4015   

TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM4015(N-benzyl-3-(2-sulfanylidene-2,3-dihydro-1H-indol-3...)
Affinity DataIC50: 9.30E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4015(N-benzyl-3-(2-sulfanylidene-2,3-dihydro-1H-indol-3...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed