BDBM401749 Cis-7-acryloyl- 2-(4- phenoxyphenyl)- 5,5a,6,7,8,8a- hexahydro-4H- pyrazolo[1,5- a]pyrrolo[3,4- e]pyrimidine-3- carboxamide::US10005782, Compound 116

SMILES NC(=O)c1c2NC[C@H]3CN(C[C@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C

InChI Key InChIKey=OZXNSRZGLKZDKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401749   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM401749(US10005782, Compound 116 | Cis-7-acryloyl- 2-(4- p...)
Affinity DataIC50: 1nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
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Date in BDB:
5/18/2020
Entry Details
US Patent