BDBM402226 2-[(9aRS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-9a- methyl-1,6,8-trioxo-4,9- dihydro-3H-pyrazino[1,2- c]pyrimidin-2-yl]thiazole- 4-carbonitrile::US10011607, 55

SMILES CC12CC(=O)N(C(=O)N1CCN(c1nc(cs1)C#N)C2=O)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=VVILZORAXINDGX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402226   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM402226(US10011607, 55 | 2-[(9aRS)-7-[2,6-difluoro-4-(2- p...)
Affinity DataEC50:  77nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent